{"id":14,"date":"2016-03-07T15:10:11","date_gmt":"2016-03-07T14:10:11","guid":{"rendered":"https:\/\/filozofia.nett.to\/psychedelika\/2016\/03\/07\/stopex-dxm-dextrometorfan-nie-je-navykovy\/"},"modified":"2026-01-28T00:44:54","modified_gmt":"2026-01-27T23:44:54","slug":"stopex-dxm-dextrometorfan-nie-je-navykovy","status":"publish","type":"post","link":"https:\/\/filozofia.nett.to\/psychedelika\/sk\/stopex-dxm-dextrometorfan-nie-je-navykovy\/","title":{"rendered":"Stopex\u200e, DXM, dextrometorfan, nie je n\u00e1vykov\u00fd"},"content":{"rendered":"

DXM celkovo funguje na princ\u00edpe \u017ee spomal\u00ed \u010dinnos\u0165 cel\u00e9ho mozgu, elektrick\u00e9 impulzy medzi nervov\u00fdmi bunkami s\u00fa omnoho slab\u0161ie.
DXM, hoci z chemick\u00e9ho h\u013eadiska je opioid, nep\u00f4sob\u00ed n\u00e1 opioidn\u00e9 receptory.
DXM m\u00e1 ve\u013emi siln\u00e9 analgetick\u00e9 \u00fa\u010dinky, av\u0161ak nie na princ\u00edpe opioidn\u00fdch receptorov. Funguje na ve\u013emi \u0161etrnom princ\u00edpe pre mozog, na b\u00e1ze antagonizmu NMDA receptorov.

Stopex\u200e, DXM, dextrometorfan, nie je potrebn\u00e9 aby bol na predpis, preto\u017ee nie je n\u00e1vykov\u00fd. V dostupn\u00fdch vedeck\u00fdch v\u00fdskumoch (v angli\u010dtine samozrejme) sa nikde nespom\u00edna, \u017ee by museli psychiatri lie\u010di\u0165 niekoho na z\u00e1vislos\u0165 na DXM. Vo vedeck\u00fdch psychiatrick\u00fdch z\u00e1znamoch sa nikde nespom\u00edna, \u017ee by mal niekto diagnostikovan\u00fa z\u00e1vislos\u0165 na DXM.

Psychiatrick\u00fd pacient:<\/strong>
Nu\u017e a ako je to s DXM? DXM u\u017e\u00edvam viac menej pod\u013ea potreby n\u00e1razovo, ke\u010f mi je \u0161patne. Vtedy, ke\u010f ma chyt\u00e1 atak depresie, \u00fazkosti, alebo ve\u013emi nepr\u00edjemn\u00e9ho stavu derealiz\u00e1cie a depersonaliz\u00e1cie. N\u00e1razovo u\u017eijem naraz aj 600 mg a na asi 6 hod\u00edn sa ponor\u00edm do ak\u00e9hosi snov\u00e9ho stavu, vn\u00edmam svet spomalene, po\u010dujem zvl\u00e1\u0161tne zvuky, akoby som bol pod vodou, je to proste tak\u00e9 zvl\u00e1\u0161tne opojenie, nie je to v\u0161ak euf\u00f3ria. Po \u0161iestich hodin\u00e1ch mi \u00fa\u010dinok pozvo\u013ene odozneje a ja za\u010d\u00ednam poci\u0165ova\u0165 \u0161tandartn\u00fd stav, ale c\u00edtim sa pritom v\u00fdrazne lep\u0161ie, tak\u00fd akoby o\u010disten\u00fd, znovuzroden\u00fd, proste stav, ak\u00fd si pam\u00e4t\u00e1m, v mladosti, ke\u010f som bol e\u0161te du\u0161evne zdrav\u00fd. Viem, \u017ee nie\u010do podobn\u00e9 poci\u0165uj\u00fa \u013eudia po elektro\u0161okoch, akur\u00e1t po DXM neregistrujem stratu pam\u00e4ti.
Raz sa mi stalo, \u017ee som u\u017eil a\u017e 1200 mg DXM a upadol som do akejsi k\u00f3my, proste som hlboko zaspal, respekt\u00edve stratil som vedomie asi na 8 hod\u00edn. Po prebrat\u00ed sa som sa c\u00edtil stra\u0161ne \u00fa\u017easne, ale nebola to euf\u00f3ria, bol to tak\u00fd povedal by som stra\u0161ne norm\u00e1lny stav, mozog som mal \u00faplne \u010dist\u00fd a svie\u017ei, neza\u0165a\u017een\u00fd \u017eiadnymi probl\u00e9mami. Proste bol som \u0161\u0165astn\u00fd, ale opakujem, nebola to euf\u00f3ria. Tento kr\u00e1sny stav norm\u00e1lnosti mi vydr\u017eal 24, a\u017e 48 hod\u00edn. Ja si mysl\u00edm, \u017ee DXM sp\u00f4sobuje nie\u010do ako tak\u00e9 chemick\u00e9 elektro\u0161oky, proste zd\u00e1 sa, \u017ee ten mechanizmus je podobn\u00fd.

V podstate v s\u00fa\u010dastnosti sa c\u00edtim ve\u013emi dobre…a ak c\u00edtim, \u017ee sa mi stav zhor\u0161uje, tak u\u017eijem DXM a stav sa mi op\u00e4\u0165 zlep\u0161\u00ed. Niekedy jednorazovo u\u017eijem aj ve\u013ek\u00e9 d\u00e1vky Coaxilu – tak 20 tabletiek a tie mi sp\u00f4sobuj\u00fa euf\u00f3riu. To je rozdiel medzi DXM a Coaxilom. DXM sp\u00f4sobuje norm\u00e1lny stav a Coaxil sp\u00f4sobuje euf\u00f3riu. Z toho usudzujem, \u017ee DXM je sk\u00f4r na potl\u00e1\u010danie psych\u00f3zy, kde\u017eto Coaxil je lep\u0161\u00ed na depresiu.

Ja:<\/em><\/strong>
Tomu antidepres\u00edvu sp\u00f4sobuje euforick\u00e9 \u00fa\u010dinky to, \u017ee p\u00f4sob\u00ed aj na opioidn\u00e9 receptory. P\u00f4sob\u00ed to teda aj proti bolesti. Ak by si chcel Coaxil vysadi\u0165, nastali by abstinen\u010dn\u00e9 pr\u00edznaky ako pri z\u00e1vislosti na opi\u00e1toch (napr. hero\u00edn, morf\u00edn). M\u00f4\u017ee\u0161 si na internete pre\u010d\u00edta\u0165 nie\u010do o z\u00e1vislosti na opi\u00e1toch a abstinen\u010dn\u00fdch pr\u00edznakoch.<\/em>

DXM samo o sebe sp\u00f4sobuje pr\u00edznaky schizofr\u00e9nie. Ale to, \u017ee ti DXM rob\u00ed dobre je pravdepodobne sp\u00f4soben\u00e9 vytvoren\u00edm tolerancie na\u0148. DXM zni\u017euje aktivitu NMDA receptorov. Mozog na DXM reaguje “protireakciou” t\u00fdm, \u017ee sa sna\u017e\u00ed zv\u00fd\u0161i\u0165 aktivitu NMDA receptorom. Po doznen\u00ed \u00fa\u010dinkov DXM sa e\u0161te st\u00e1le mozog zna\u017e\u00ed zvy\u0161ova\u0165 aktivitu NMDA receptorom a NMDA receptory s\u00fa st\u00e1le vo svojej nadpriemernej aktivite, \u010do poci\u0165uje\u0161 tak, \u017ee sa c\u00edti\u0161 dobre.<\/em>

PS: v\u0161imnite si ako aj tento pacient potvrdil, \u017ee DXM nie je n\u00e1vykov\u00e1 l\u00e1tka. Zauj\u00edmav\u00e9 ako porovn\u00e1va n\u00e1vykov\u00fd liek s nen\u00e1vykov\u00fdm. Je to zauj\u00edmav\u00e9 porovnanie<\/em><\/strong>
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NMDA antagonista, DXM, dostupn\u00fd aj na Slovensku,
dostupn\u00fd vo\u013ene, bez lek\u00e1rskeho predpisu

Stopex na vyka\u0161liavanie, tbl eff 20×60 mg

http:\/\/www.sukl.sk\/buxus\/generate_page.php?page_id=386&lie_id=21060<\/a>

https:\/\/en.wikipedia.org\/wiki\/Recreational_use_of_dextromethorphan<\/a>
https:\/\/en.wikipedia.org\/wiki\/Dextromethorphan<\/a>
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In\u00fd \u010dlovek z \u010cR mi nap\u00edsal tak\u00e9to svedectvo. Hoci tento \u010dlovek m\u00e1 schizofr\u00e9niu a depresie, aj napriek tomu mu DXM neu\u0161kodilo, naopak sk\u00f4r ho vylie\u010dilo, resp. pomohlo mu zvl\u00e1da\u0165 diagn\u00f3zu lep\u0161ie

4. 1. 2016
M\u00e1m n\u011bco zaj\u00edmav\u00e9ho . Po probd\u011bl\u00e9 noci jsem \u0161el r\u00e1no cca v 6 sp\u00e1t a z n\u011bjak\u00e9ho d\u016fvodu jsem si vzal op\u011bt Stopex, nev\u00edm co m\u011b to napadlo , ale to je fuk . Vzal jsem si 11×30 mg a \u0161el sp\u00e1t . Bo\u017ee , to bylo tak dokonal\u00e9 ! Byl jsem na jin\u00e9 planet\u011b , byl mimo \u010das , putoval vesm\u00edrem , vid\u011bl minul\u00e9 pozemsk\u00e9 \u017eivoty \u010dlen\u016f rodiny ….. V\u00edm , \u017ee to byli asi jenom haldy , ale oproti minule to bylo \u00fa\u017easn\u00fd ! Na za\u010d\u00e1tku jsem zkou\u0161el pro\u010distit temeno a pak upadl do toho stavu …. A i na konci jsem pro\u010di\u0161\u0165oval a \u0161lo to jako po m\u00e1sle . M\u00e1m pocit , \u017ee se tam d\u011blo n\u011bco , po \u010dem bych mohl zvl\u00e1dnou LD , nebo m\u00e1m alespo\u0148 ten pocit … a s tou dne\u0161n\u00ed meditac\u00ed ? Dokonal\u00fd !

Dobr\u00e9 bylo , \u017ee jsem nebyl vzh\u016fru , respektive nem\u011bl jsem otev\u0159en\u00e9 o\u010di , le\u017eel jsem a poddal se tomu . Jedin\u00e1 nev\u00fdhoda byla ( nebo mi to tak p\u0159i\u0161lo ) j\u00edt na z\u00e1chod , p\u0159i t\u00e9to d\u00e1vce jsem m\u011bl co d\u011blat udr\u017eet se na nohou . Nav\u00edc \u010dlov\u011bk ud\u011bl\u00e1 p\u00e1r krok\u016f a nev\u00ed co cht\u011bl a p\u0159\u00edjde mu jako hodiny co ud\u011blal prvn\u00ed krok , zkr\u00e1tka se dost \u0161t\u011bp\u00ed realita , co\u017e p\u0159i prvn\u00edm m\u00e9m z\u00e1\u017eitku nebylo to prav\u00e9 o\u0159echov\u00e9. Ale minule jsi radil , \u017ee \u010dlov\u011bk m\u00e1 le\u017eet a nechat ty sny sn\u00edt . Nem\u011bl jsem ani stihomam ani deprese , bylo to opravdu kr\u00e1sn\u00fd .
U\u017e jenom z psychologick\u00e9ho hlediska to je dobr\u00e9 , m\u00edt pocit , \u017ee ka\u017edodenn\u00ed z\u00e1le\u017eitosti jsou jako iluze . Jak jsi psal , m\u00e9n\u011b a m\u00e9n\u011b utrpen\u00ed . Ani se nebudu b\u00e1t d\u00e1t si v\u011bt\u0161\u00ed d\u00e1vku , ale a\u017e tak za dva t\u00fddny , jinak by to bylo zbyte\u010dn\u00e9 .

10. 12. 2015
Ja:<\/em><\/strong>
DXM je v celku \u0161etrn\u00e9 na mozog a nem\u00e1 nejak\u00e9 rizik\u00e1 okrem t\u00fdch depresi\u00ed, ktor\u00e9 si mal pri prvom u\u017eit\u00ed (zas naopak ist\u00e1 \u017eena mi hovorila \u017ee jej DXM pozit\u00edvne p\u00f4sobilo na \u00fazkos\u0165 (\u00fazkos\u0165 je in\u00e1 diagn\u00f3za ako depresia)). Niektor\u00e9 lieky a niektor\u00e9 kombin\u00e1cie liekov ktor\u00e9 predpisuj\u00fa psychiatri u\u017e zdravotn\u00e9 rizik\u00e1 maj\u00fa – aj v\u00e4\u010d\u0161ie.
Na \u010dloveka so schizofr\u00e9niou p\u00f4sob\u00ed DXM o nie\u010do silnej\u0161ie, \u010do je v tomto pr\u00edpade v\u00fdhoda.
Depresie vznikaj\u00fa kv\u00f4li tomu, \u017ee niektor\u00e9 centr\u00e1 v mozgu s\u00fa m\u00e1lo akt\u00edvne. DXM zni\u017euje aktivitu cel\u00e9mu mozgu, preto sa ti pr\u00edznaky depresi\u00ed zhor\u0161ili, ke\u010f si bol pod vplyvom.<\/p>\n

Aktualiz\u00e1cia, oprava (september 2018):<\/span><\/strong> DXM predsa len m\u00f4\u017ee by\u0165 n\u00e1vykov\u00fd nako\u013eko m\u00e1 tie\u017e dos\u0165 siln\u00fa afinitu na \u03bc-opioidn\u00fd receptor. Na psychedelick\u00fdch vlastnostiach sa okrem glutam\u00e1tov\u00fdch NMDA receptoroch v\u00fdznamne podie\u013eaj\u00fa aj sigma-1 receptory. Pre porovnanie na sigma-1 receptory p\u00f4sob\u00ed aj popul\u00e1rne DMT (= \u201eajavaska\u201c)<\/p>","protected":false},"excerpt":{"rendered":"DXM celkovo funguje na princ\u00edpe \u017ee spomal\u00ed \u010dinnos\u0165 cel\u00e9ho mozgu, elektrick\u00e9 impulzy medzi nervov\u00fdmi bunkami s\u00fa omnoho slab\u0161ie. DXM, hoci z chemick\u00e9ho h\u013eadiska je opioid, nep\u00f4sob\u00ed n\u00e1 opioidn\u00e9 receptory. NMDA antagonista, DXM, dostupn\u00fd aj na Slovensku, dostupn\u00fd vo\u013ene, bez lek\u00e1rskeho predpisu.","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[],"class_list":["post-14","post","type-post","status-publish","format-standard","hentry","category-psychedelika"],"_links":{"self":[{"href":"https:\/\/filozofia.nett.to\/psychedelika\/wp-json\/wp\/v2\/posts\/14","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/filozofia.nett.to\/psychedelika\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/filozofia.nett.to\/psychedelika\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/filozofia.nett.to\/psychedelika\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/filozofia.nett.to\/psychedelika\/wp-json\/wp\/v2\/comments?post=14"}],"version-history":[{"count":0,"href":"https:\/\/filozofia.nett.to\/psychedelika\/wp-json\/wp\/v2\/posts\/14\/revisions"}],"wp:attachment":[{"href":"https:\/\/filozofia.nett.to\/psychedelika\/wp-json\/wp\/v2\/media?parent=14"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/filozofia.nett.to\/psychedelika\/wp-json\/wp\/v2\/categories?post=14"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/filozofia.nett.to\/psychedelika\/wp-json\/wp\/v2\/tags?post=14"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}