{"id":32,"date":"2017-03-13T21:10:07","date_gmt":"2017-03-13T20:10:07","guid":{"rendered":"https:\/\/filozofia.nett.to\/farmakologia\/2017\/03\/13\/liecba-adhd-seleginom-podrobne-prepracovane-farmakologicke-moznosti-liecby-adhd\/"},"modified":"2026-01-30T17:29:05","modified_gmt":"2026-01-30T16:29:05","slug":"liecba-adhd-seleginom-podrobne-prepracovane-farmakologicke-moznosti-liecby-adhd","status":"publish","type":"post","link":"https:\/\/filozofia.nett.to\/farmakologia\/sk\/liecba-adhd-seleginom-podrobne-prepracovane-farmakologicke-moznosti-liecby-adhd\/","title":{"rendered":"Lie\u010dba ADHD seleg\u00ednom. Podrobne prepracovan\u00e9 farmakologick\u00e9 mo\u017enosti lie\u010dby ADHD"},"content":{"rendered":"

Tento \u010dl\u00e1nok s\u00fa \u00faryvky s konverz\u00e1cie so psychyatrick\u00fdm pacientom star\u0161\u00edm ako 18 rokov, trpiaci poruchou pozornosti s hyperaktivitou, hyperkinetickou poruchou<\/strong><\/p>\n

Metamfeman\u00edn (=pervit\u00edn) je v USA americkou FDA ofici\u00e1lne indikovan\u00fd na ADHD vo farmakologickej forme lieku. Zdrojhttps:\/\/en.wikipedia.org\/wiki\/Methamphetamine#Uses<\/a><\/p>\n

Mo\u017eno aj liek CONCERTA (=metylfenid\u00e1t) by ti mohli predp\u00edsa\u0165. Ofici\u00e1lne lie\u010dba sa mus\u00ed za\u010da\u0165 vo veku menej ako 18 rokov a potom m\u00f4\u017ee pokra\u010dova\u0165 aj vo vy\u0161\u0161om veku. S t\u00fdmto by si bol tie\u017e spokojn\u00fd, len je to len do veku 18 rokov – lek\u00e1ri to maj\u00fa zak\u00e1zan\u00e9 pre star\u0161\u00edch. A tie\u017e ide o n\u00e1vykov\u00fa l\u00e1tku <\/p>\n

Tento liek je na ADHD ide\u00e1lny preto\u017ee selekt\u00edvne p\u00f4sob\u00ed na to \u010do treba: zvy\u0161uje aktivitu dopam\u00ednov\u00fdm a noradrenal\u00ednov\u00fdm receptoromhttp:\/\/www.sukl.sk\/buxus\/generate_page.php?page_id=386&lie_id=49926<\/a><\/p>\n

https:\/\/en.wikipedia.org\/wiki\/Methylphenidate#Pharmacology<\/a><\/p>\n

Toto zvy\u0161uje aktivitu noradrenal\u00ednov\u00fdm receptorom. Na pr\u00edbalovom let\u00e1\u010diku je nap\u00edsan\u00e9, \u017ee je to na ADHD. Ale nebude to tak\u00e9 dobr\u00e9 ako ten hore uveden\u00fd liek. Ve\u013ek\u00e1 \u0161koda \u017ee nep\u00f4sob\u00ed aj na dopam\u00ednov\u00e9 receptory, preto\u017ee za ADHD zodpoved\u00e1 n\u00edzka aktivita dopam\u00ednov\u00fdch receptorov https:\/\/www.adc.sk\/databazy\/produkty\/detail\/atomoxetine-actavis-10-mg-517380.html<\/a><\/p>\n

Tianept\u00edn, hoci je to trochu sporn\u00e9, by mal trochu zvy\u0161ova\u0165 aktivitu dopam\u00ednov\u00fdm receptorom, tak\u017ee m\u00e1 pozit\u00edvny vplyv na ADHDhttps:\/\/www.adc.sk\/databazy\/produkty\/pil\/tianeptin-sandoz-12-5-mg-filmom-obalene-tablety-308557.html<\/a><\/p>\n

https:\/\/en.wikipedia.org\/wiki\/Tianeptine#Mechanism_of_action<\/a><\/p>\n

To \u00e1no, tvoja sk\u00fasenos\u0165 sa zhoduje aj s vedeck\u00fdmi poznatkami. Pozeral som vedeck\u00e9 v\u00fdskumy o \u00fa\u010dinnej l\u00e1tke mu\u0161k\u00e1tov\u00e9ho orie\u0161ku a jeho \u00fa\u010dinok je rovnak\u00fd ako u liekov ktor\u00e9 s\u00fa MAOI (IMAO).<\/p>\n

https:\/\/en.wikipedia.org\/wiki\/Nutmeg#Psychoactivity_and_toxicity<\/a><\/p>\n

IMAO A posobia na serotoninove a noradrenalinove receptory – zvysuju im aktivitu, kym IMAO B zvysuju aktivitu hlavne na dopaminove receptory.<\/p>\n

Hlavny ucinok pervitinu je zvysovanie aktivity dopaminovym receptorom. IMAO B maju prevazne vyuzitie pre parkinsonikov. Takmer vsetky lieky pre parkinsonikov su zalozenie na zvysovani aktivity dopaminvych receptorov. IMAO A by ti pomohlo jedine vo zvyseni aktivity noradrenalinovych receptorov.<\/p>\n

Selegil\u00edn nem\u00e9 \u017eiadne v\u00e1\u017ene ved\u013eaj\u0161ie \u00fa\u010dinky. Toto nie je liek, ktor\u00fd by mal v\u00fdznamne ved\u013eaj\u0161ie \u00fa\u010dinky, nie je treba \u017eiadna di\u00e9ta, to je in\u00fd druh IMAO.<\/p>\n

….Nebol by v tom probl\u00e9m aby ti predp\u00edsali MAO B selegil\u00edn.<\/p>\n

… Existuj\u00fa aj vedeck\u00e9 v\u00fdskumy, ktor\u00e9 dokazuj\u00fa, \u017ee teto liek je v\u00fdborn\u00fd ho pou\u017ei\u0165 na ADHD. Ve\u013emi \u00fa\u010dinne zvy\u0161uje aktivitu dopam\u00ednov\u00fdch receptorom, trochu zvy\u0161uje aktivitu aj adrenal\u00ednov\u00fdm receptorom v mozgu. A zdlhodob\u00e9ho h\u013eadiska je to ve\u013emi \u0161etrnn\u00fd liek.<\/p>\n

https:\/\/en.wikipedia.org\/wiki\/Selegiline#Pharmacology<\/a><\/p>\n

Z\u00e1ver vedeck\u00e9ho v\u00fdskumu dokazuje, \u017ee selegil\u00edn je vhodn\u00fd na lie\u010dbu ADHD https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12921918<\/a><\/p>\n

V\u00fdhoda selegil\u00ednu je \u017ee nie je n\u00e1vykovou l\u00e1tkou.<\/p>\n

Selegil\u00edn na webstr\u00e1nke SUKL<\/p>\n

http:\/\/www.sukl.sk\/sk\/databazy-a-servis\/databazy\/vyhladavanie-v-databaze-registrovanych-liekov?page_id=242&lie_nazov=&lie_kod=&atc_kod=&lie_rc=&atc_nazov=selegil%C3%ADn&isk_kod=0&drz_kod=&vyd_kod=0&org_kod=0&reg_typ_kod=0&in_kat=LEFT&ped_ind=ALL&ped_kontraind=ALL<\/a><\/p>\n

https:\/\/www.adc.sk\/databazy\/produkty\/klasifikacia\/HLN04BD01\/selegilin.html<\/a><\/p>\n

https:\/\/www.adc.sk\/databazy\/produkty\/detail\/selegil-5mg-365949.html<\/a><\/p>\n

Ano ale myslis ze seleginil mi pomoze? Je to na tebe co mu poradis no ja som vzdy myslel ze trebars tie zvycajne ako modafinil. <\/em><\/strong><\/p>\n

Diki za pripomenutie. To \u00e1no aj modafinil by bol dobr\u00fd, zvy\u0161uje aktivitu dopam\u00ednov\u00fdm receptorom. Jeho nev\u00fdhoda je v tom, \u017ee jedna tableta m\u00e1 100 mg \u00fa\u010dinnej l\u00e1tky.<\/strong><\/p>\n

Selegil\u00edn je viac \u00fa\u010dinn\u00e1 l\u00e1tka: jedna tableta m\u00e1 5 mg, tak\u017ee je trochu viac \u0161etrn\u00fd na pe\u010de\u0148. Ak by si mal nejak\u00e9 v\u00e1\u017enej\u0161ie ved\u013eaj\u0161ie \u00fa\u010dinky so selegil\u00ednu, tak aj modafinil by bol dobr\u00fd. Oboje lieky s\u00fa dobr\u00e9.<\/p>","protected":false},"excerpt":{"rendered":"Tento \u010dl\u00e1nok s\u00fa \u00faryvky s konverz\u00e1cie so psychyatrick\u00fdm pacientom star\u0161\u00edm ako 18 rokov, trpiaci poruchou pozornosti s hyperaktivitou, hyperkinetickou poruchou","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[],"class_list":["post-32","post","type-post","status-publish","format-standard","hentry","category-farmakologia"],"_links":{"self":[{"href":"https:\/\/filozofia.nett.to\/farmakologia\/wp-json\/wp\/v2\/posts\/32","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/filozofia.nett.to\/farmakologia\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/filozofia.nett.to\/farmakologia\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/filozofia.nett.to\/farmakologia\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/filozofia.nett.to\/farmakologia\/wp-json\/wp\/v2\/comments?post=32"}],"version-history":[{"count":0,"href":"https:\/\/filozofia.nett.to\/farmakologia\/wp-json\/wp\/v2\/posts\/32\/revisions"}],"wp:attachment":[{"href":"https:\/\/filozofia.nett.to\/farmakologia\/wp-json\/wp\/v2\/media?parent=32"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/filozofia.nett.to\/farmakologia\/wp-json\/wp\/v2\/categories?post=32"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/filozofia.nett.to\/farmakologia\/wp-json\/wp\/v2\/tags?post=32"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}