It's probably not necessary to say what crap benzodiazepines/sedatives are, as tolerance to them develops extremely quickly, and in addition to psychological dependence, physical dependence also develops. Then doctors might as well prescribe heroin for anxiety; sedatives have no less addictive potential than heroin.
Some antiepileptic drugs that are selective agonists of GABA receptors are better.
https://en.wikipedia.org/wiki/Benzodiazepine
SSRI
SSRIs also have their minor disadvantages. There are many types of serotonin receptors, and SSRIs act on all types, even those that have no effect on depression.
https://en.wikipedia.org/wiki/5-HT_receptor#Families
One of the types of serotonin receptors even has the property that its increased activity will reduce the activity of other serotonin receptors, which may not be desirable (but these are only negligible side effects). This may explain the weaker efficacy of SSRI drugs than would be expected in some cases.
And as far as I know, according to official statistics, SSRIs help only 50% of patients, which is quite low. We already have significantly better drugs than Buspirone on the Slovak market.
Combining antipsychotics that are agonists for serotonin receptors has its risks and should be done with increased caution (I'm afraid that the miserable amateur ŠÚKL does not warn about this). The SSRI dose should be significantly lower in such a case.
Buspirone (Spitomin)
This drug should definitely be the first choice for anxiety and depression. Although it is officially intended only for anxiety, it will also be good for depression. The principle of its functioning is agonism on some serotonin receptors.
This medicine is probably not suitable for combination with antipsychotics that are agonists of the same serotonin receptors as buspirone.
http://www.sukl.sk/buxus/generate_page.php?page_id=386&lie_id=14967
http://www.sukl.sk/buxus/generate_page.php?page_id=386&lie_id=14968
https://en.wikipedia.org/wiki/Buspirone
Tofisopam (Grandaxin)
It is an atypical benzodiazepine that does not have the properties of benzodiazepines. However, whether it has anti-anxiety properties is debatable. It should probably not be addictive.
Mirtazapine, (Mirzaten)
http://en.wikipedia.org/wiki/Mirtazapine
It is not a reuptake inhibitor.
It is indicated for depression. It is a serotonin receptor antagonist and, ultimately, in a complex action, it increases the activity of the adrenaline receptor.
It is interesting that even an antagonist of serotonin receptors can have anti-anxiety effects. If a patient is not helped by, for example, an SSRI, then trying this drug can be an interesting choice.
Vortioxetine (Brintellix)
https://en.wikipedia.org/wiki/Vortioxetine
It is an atypical inhibitor of serotonin and noradrenaline reuptake. It is an agonist for some serotonin receptors and an antagonist for others. There will likely be significant differences between short-term and long-term use of this drug; it is clear that the inhibition of reuptake will only manifest after a certain period of use.
Bupropion (Wellbutrin)
Norepinephrine and dopamine reuptake inhibitor. In higher doses, it also has several negative side effects – the most serious being epilepsy.
This drug probably does not increase blood pressure much, as it should be an antagonist of adrenaline receptors.
On a side note: By the way, a French pharmaceutical company once produced a selective dopamine reuptake inhibitor with a strong effect (I don't remember the name of the drug, but it could be found). This drug was extremely addictive (like some kind of methamphetamine), so it was later withdrawn.